Thalassaemia

Thalassaemia


Thalassaemia ko doctor Thomson ban teen Cooley or on k sathi lee ny 1925 meh duryaaft Keya or esy Thalassaemia ka nam deya or unaani zobaan meh thalassa ka mutlub somondur hy or aemia ki mani blood hen es leye esko Thalassaemia kaha jata hy or es k elawa doctor cooley k nam sy be esy yad Keya jata hy ku k ono ny es py bot kam Keya es leye essy cooley anaemia bhe kehty hen.

Thalassaemia ek tura ki blood ki bemaari hy jis meh red blood cells R.B.C mokamal ni ho paty or apna life time pora hony say phalli he tubah ho jaty hen ye bemari ek turaa ki wurassti bemari hy yani ky Genetic disorder ki waja sy chulti arhi hy.Thalassameia meh Hemoglobin ka structure motasir hota h es k leye hemoglobin k structure ko study kurty hen first.

Haemoglobin ky du hissy hoty hen ek hisaa Heam kheh-lata hy jo ky Fe 2+ atom py mosh-tamil hota hy or dosraa hisaa eska Globin keh-lata hy jo ky protein pur mosh-at-mil hota hy es turra haemoglobin meh ye he protein polypepide chain ki shukal meh paya jata hy jis k undur du alfa chain or du beta chain hoty hen so en polypeptide chain meh tub-deeli ki waja sy Thalassameia wujod meh ati hy es ki agy du types hen

B thalassaemia ya beta Thalassaemia

Beta peptide chains meh tub-deeli ki waja s yes disease ko B Thalassaemia kehty hen or agur es meh beta chains mojood he na ho tu esy Thalassaemia major kehty hen jo k khutarnaak kissam hy or dosri kissum meh beta chain kum ya udhora hota hy tu es type ko thalassaemia minor kehty hen.thalassaemia minor ky mureez ki zindgi koi koi khutra ni hota bhurpoor zinidgi gozarty hen es tura Pakistan meh es wukat Thalassaemia minor ky carries 7% hen so jub itfakun jub in ki apus meh shadi ho jati hy tu pher Thalassaemia major k murez baby pada hoty hen.

Alfa Thalassaemia

Agur disease meh alfa chains meh changing ho tu esy alfa Thalassaemia kehty hen ziyada tur Thalassaemia minor wujood meh aty hen.Alfa chain jo hy ye 4 jenes ki wuja sy bunta hy or jub ye four jenes meh problem ho jata hy tu thalasaemia major wujood meh ata hy or pher ess turaa pher normal haemoglobin produce ni ho pati

Thalassameia ky mureez meh chund symptoms ko physically dyka ja sukta hy jesy

· Blood ki kumi ki waja sy oska colure peela yani yellowish ho ghaa

· Face gol or mota ho ghaa

· Iron ki kumi ki waja sy teeth black hongy

· Heart beat tazz or fever b ho sukta hy

· Blood ki kumi ki waja sy saanss ki tukleef ho ghe

· Hath sy tut-tolny sy spleen or liver buraa howa mehsoos ho ga

Thalassameia ziyada tu villages or pusmandaa elaaqoo meh paya jata hy jahaa py cousin marriage ka ruwaaj aam hy ek undazy k motaabik Pakistan meh hur saal 5 thousend children Thalassaemia ki bemari meh bomtillah ho ry hen or Pakistan ki population meh 5 sy 7% people Thalassaemia minor meh bobtilah hen or Pakistan meh Thalassaemia major ki mureez buchy tu apni first age meh he mur jaty hen or moshkil sy Thalassaemia major k murez 10 saal tuk jee paty hem.thalassaemia minor meh bobtilalh women or man dono ko apus meh shadi ni kurni chaiye

Thalassaemia meh mob-tilah bucho ko umomun 3 chaar hufto bhad blood transfusion ki zroorat purti hy ku k bucho meh blood pada ni hota or onki zindgi ka inhisaaar blood py he hota hy abi tuk ye beemari la elaaj hy serf blood day k murez ko zinda rukha jata hy or eska elaaj bot costly hy

Thalassaemia meh bone marrow transplant Pakistan meh kafi costly hy tukreebun 12 sy 14 lakh lug jaty hen or bone marrow transplant k leye healthy donor ki zrorut hoti hy lakin Pakistan meh bone marrow transplant ka success rate 60 at 70 % hy

Cousin marriage kurny waly shadi sy phaly apny blood test kurwayin , bood study kurwain so agur Thalassaemia minor k carrier hen tu shadi ni kurin or agur shadi kur laty hen tu pher baby pada na kurin or agur Thalassaemia major ka baby paydaa ho choka hy tu or baby paydaa ni kruin.